Main structural chromosomal variations are detectable by karyotyping, though the microarray can’t detect larger copy quantity variations of 10 or 20Kb. 

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So we are able to say that while the karyotyping system is laborous and time-consuming, it is simple. Although the microarray technique is intricate and depends on hybridization. 

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Mutations is usually a result of mistakes during DNA replication or by exterior things like radiation or chemical substances. Most mutations are neutral or unsafe, but some can confer a benefit in a particular setting.

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DNA just isn't expected in karyotyping but a top quality DNA sample is required in an effort to get superior results during microarray analysis. 

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Within a mobile, DNA is arranged into dense protein-DNA complexes identified as chromosomes. In eukaryotes, the chromosomes are located while in the nucleus, Though DNA also is found in mitochondria and chloroplasts. In prokaryotes, which tend not to have a membrane-bound nucleus, the DNA is found as a single round chromosome while in the cytoplasm.

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